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GWAS Study

A comprehensive evaluation of the genetic architecture of sudden cardiac arrest.

Ashar FN, Mitchell RN, Albert CM et al.

30169657 PubMed ID
GWAS Study Type
71013 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

AF
Ashar FN
MR
Mitchell RN
AC
Albert CM
NC
Newton-Cheh C
BJ
Brody JA
MM
Müller-Nurasyid M
MA
Moes A
MT
Meitinger T
MA
Mak A
HH
Huikuri H
JM
Junttila MJ
GP
Goyette P
PS
Pulit SL
PR
Pazoki R
TM
Tanck MW
BM
Blom MT
ZX
Zhao X
HA
Havulinna AS
JR
Jabbari R
GC
Glinge C
TV
Tragante V
ES
Escher SA
CA
Chakravarti A
EG
Ehret G
CJ
Coresh J
LM
Li M
PR
Prineas RJ
FO
Franco OH
KP
Kwok PY
LT
Lumley T
DF
Dumas F
MB
McKnight B
RJ
Rotter JI
LR
Lemaitre RN
HS
Heckbert SR
OC
O'Donnell CJ
HS
Hwang SJ
TJ
Tardif JC
VM
VanDenburgh M
UA
Uitterlinden AG
HA
Hofman A
SB
Stricker BHC
DB
de Bakker PIW
FP
Franks PW
JJ
Jansson JH
AF
Asselbergs FW
HM
Halushka MK
MJ
Maleszewski JJ
TJ
Tfelt-Hansen J
ET
Engstrøm T
SV
Salomaa V
VR
Virmani R
KF
Kolodgie F
WA
Wilde AAM
TH
Tan HL
BC
Bezzina CR
EM
Eijgelsheim M
RJ
Rioux JD
JX
Jouven X
KS
Kääb S
PB
Psaty BM
SD
Siscovick DS
AD
Arking DE
SN
Sotoodehnia N
Chapter II

Abstract

Summary of the research findings

Aims: Sudden cardiac arrest (SCA) accounts for 10% of adult mortality in Western populations. We aim to identify potential loci associated with SCA and to identify risk factors causally associated with SCA.

up to 3,939 European ancestry cases, up to 25,989 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

71013
Total Participants
GWAS
Study Type
Yes
Replicated
up to 4,751 European ancestry cases, up to 35,582 European ancestry controls, 152 African American cases, 176 African American controls, 225 Asian American cases, 199 Asian American controls
Replication Participants
African American or Afro-Caribbean, European, Asian unspecified, European, African unspecified, Asian unspecified
Ancestry
U.S., France, Germany, Netherlands, Finland, Denmark, Sweden
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.