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Genomic profiling in advanced stage non-small-cell lung cancer patients with platinum-based chemotherapy identifies germline variants with prognostic value in SMYD2.

Galván-Femenía I, Guindo M, Duran X et al.

30207284 PubMed ID
GWAS Study Type
537 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

GI
Galván-Femenía I
GM
Guindo M
DX
Duran X
CS
Calabuig-Fariñas S
MJ
Mercader JM
RJ
Ramirez JL
RR
Rosell R
TD
Torrents D
CA
Carreras A
KT
Kohno T
JE
Jantus-Lewintre E
CC
Camps C
PM
Perucho M
SL
Sumoy L
YJ
Yokota J
DC
de Cid R
Chapter II

Abstract

Summary of the research findings

Objective: The aim of the study was to investigate the relationship between germline variations as a prognosis biomarker in patients with advanced Non-Small-Cell-Lung-Cancer (NSCLC) subjected to first-line platinum-based treatment.

181 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

537
Total Participants
GWAS
Study Type
Yes
Replicated
356 European ancestry individuals
Replication Participants
European
Ancestry
Spain
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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