Very low-depth whole-genome sequencing in complex trait association studies.
Gilly A, Southam L, Suveges D et al.
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Motivation: Very low-depth sequencing has been proposed as a cost-effective approach to capture low-frequency and rare variation in complex trait association studies. However, a full characterization of the genotype quality and association power for very low-depth sequencing designs is still lacking.
1,225 Mylopotamos (founder/genetic isolate) individuals
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