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GWAS Study

Genetic risk score combining six genetic variants associated with the cellular NRF2 expression levels correlates with Type 2 diabetes in the human population.

Shin JH, Lee KM, Shin J et al.

30767168 PubMed ID
GWAS Study Type
74 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SJ
Shin JH
LK
Lee KM
SJ
Shin J
KK
Kang KD
NC
Nho CW
CY
Cho YS
Chapter II

Abstract

Summary of the research findings

Type 2 diabetes (T2D) is known as an inflammatory disease. NRF2 (Nuclear Factor Erythroid 2 Like2) encodes a transcription factor that binds to antioxidant response elements (AREs) and regulates the expression of genes involved in many antioxidant responses.

74 East Asian ancestry lymphoblastoid cell lines

Chapter III

Study Statistics

Key metrics and study information

74
Total Participants
GWAS
Study Type
No
Replicated
East Asian
Ancestry
Republic of Korea
Recruitment Country
Chapter IV

AI-Generated Summary

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