The 2018 Otto Aufranc Award: How Does Genome-wide Variation Affect Osteolysis Risk After THA?
MacInnes SJ, Hatzikotoulas K, Fenstad AM et al.
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Abstract
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Periprosthetic osteolysis resulting in aseptic loosening is a leading cause of THA revision. Individuals vary in their susceptibility to osteolysis and heritable factors may contribute to this variation. However, the overall contribution that such variation makes to osteolysis risk is unknown.
1,096 European ancestry cases, 2,418 European ancestry controls
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