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GWAS Study

Clinical and Genome-Wide Analysis of Cisplatin-Induced Tinnitus Implicates Novel Ototoxic Mechanisms.

El Charif O, Mapes B, Trendowski MR et al.

30952644 PubMed ID
GWAS Study Type
762 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

EC
El Charif O
MB
Mapes B
TM
Trendowski MR
WH
Wheeler HE
WC
Wing C
DP
Dinh PC
FR
Frisina RD
FD
Feldman DR
HR
Hamilton RJ
VD
Vaughn DJ
FC
Fung C
KC
Kollmannsberger C
MT
Mushiroda T
KM
Kubo M
GE
Gamazon ER
CN
Cox NJ
HR
Huddart R
AS
Ardeshir-Rouhani-Fard S
MP
Monahan P
FS
Fossa SD
EL
Einhorn LH
TL
Travis LB
DM
Dolan ME
Chapter II

Abstract

Summary of the research findings

Purpose: Cisplatin, a commonly used chemotherapeutic, results in tinnitus, the phantom perception of sound. Our purpose was to identify the clinical and genetic determinants of tinnitus among testicular cancer survivors (TCS) following cisplatin-based chemotherapy.

154 European ancestry cases, 608 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

762
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Canada, U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

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