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GWAS Study

Pilot GWAS of caries in African-Americans shows genetic heterogeneity.

Orlova E, Carlson JC, Lee MK et al.

31533690 PubMed ID
GWAS Study Type
109 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

OE
Orlova E
CJ
Carlson JC
LM
Lee MK
FE
Feingold E
MD
McNeil DW
CR
Crout RJ
WR
Weyant RJ
MM
Marazita ML
SJ
Shaffer JR
Chapter II

Abstract

Summary of the research findings

Dental caries is the most common chronic disease in the US and disproportionately affects racial/ethnic minorities. Caries is heritable, and though genetic heterogeneity exists between ancestries for a substantial portion of loci associated with complex disease, a genome-wide association study (GWAS) of caries specifically in African Americans has not been performed previously.

109 African American adults

Chapter III

Study Statistics

Key metrics and study information

109
Total Participants
GWAS
Study Type
No
Replicated
African American or Afro-Caribbean
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

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