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GWAS Study

Genome wide association study of apparent treatment resistant hypertension in the CHARGE consortium: The CHARGE Pharmacogenetics Working Group.

Irvin MR, Sitlani CM, Floyd JS et al.

31545351 PubMed ID
GWAS Study Type
17849 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

IM
Irvin MR
SC
Sitlani CM
FJ
Floyd JS
PB
Psaty BM
BJ
Bis JC
WK
Wiggins KL
WE
Whitsel EA
ST
Sturmer T
SJ
Stewart J
RL
Raffield L
SF
Sun F
LC
Liu CT
XH
Xu H
CA
Cupples AL
TR
Tanner RM
RP
Rossing P
SA
Smith A
ZN
Zilhão NR
LL
Launer LJ
NR
Noordam R
RJ
Rotter JI
YJ
Yao J
LX
Li X
GX
Guo X
LN
Limdi N
SA
Sundaresan A
LL
Lange L
CA
Correa A
SD
Stott DJ
FI
Ford I
JJ
Jukema JW
GV
Gudnason V
MD
Mook-Kanamori DO
TS
Trompet S
PW
Palmas W
WH
Warren HR
HJ
Hellwege JN
GA
Giri A
OC
O'donnell C
HA
Hung AM
ET
Edwards TL
AT
Ahluwalia TS
AD
Arnett DK
AC
Avery CL
Chapter II

Abstract

Summary of the research findings

Only a handful of genetic discovery efforts in apparent treatment-resistant hypertension (aTRH) have been described.

931 European ancestry cases, 228 African American ancestry cases, 14,210 European ancestry controls, 2,480 African American ancestry controls

Chapter III

Study Statistics

Key metrics and study information

17849
Total Participants
GWAS
Study Type
Yes
Replicated
11,762 European ancestry cases, 42,850 European ancestry controls
Replication Participants
European, African American or Afro-Caribbean
Ancestry
Netherlands, Denmark, Iceland, Republic of Ireland, U.K., U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

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