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GWAS Study

Genome wide association study of apparent treatment resistant hypertension in the CHARGE consortium: The CHARGE Pharmacogenetics Working Group.

Irvin MR, Sitlani CM, Floyd JS et al.

31545351 PubMed ID
GWAS Study Type
17849 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

IM
Irvin MR
SC
Sitlani CM
FJ
Floyd JS
PB
Psaty BM
BJ
Bis JC
WK
Wiggins KL
WE
Whitsel EA
ST
Sturmer T
SJ
Stewart J
RL
Raffield L
SF
Sun F
LC
Liu CT
XH
Xu H
CA
Cupples AL
TR
Tanner RM
RP
Rossing P
SA
Smith A
ZN
Zilhão NR
LL
Launer LJ
NR
Noordam R
RJ
Rotter JI
YJ
Yao J
LX
Li X
GX
Guo X
LN
Limdi N
SA
Sundaresan A
LL
Lange L
CA
Correa A
SD
Stott DJ
FI
Ford I
JJ
Jukema JW
GV
Gudnason V
MD
Mook-Kanamori DO
TS
Trompet S
PW
Palmas W
WH
Warren HR
HJ
Hellwege JN
GA
Giri A
OC
O'donnell C
HA
Hung AM
ET
Edwards TL
AT
Ahluwalia TS
AD
Arnett DK
AC
Avery CL
Chapter II

Abstract

Summary of the research findings

Only a handful of genetic discovery efforts in apparent treatment-resistant hypertension (aTRH) have been described.

931 European ancestry cases, 228 African American ancestry cases, 14,210 European ancestry controls, 2,480 African American ancestry controls

Chapter III

Study Statistics

Key metrics and study information

17849
Total Participants
GWAS
Study Type
Yes
Replicated
11,762 European ancestry cases, 42,850 European ancestry controls
Replication Participants
European, African American or Afro-Caribbean
Ancestry
Netherlands, Denmark, Iceland, Republic of Ireland, U.K., U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.