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GWAS Study

A Novel Susceptibility Locus Near GRIK2 Associated With Erosive Esophagitis in a Korean Cohort.

Jin EH, Park B, Kim YS et al.

32132452 PubMed ID
GWAS Study Type
4242 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

JE
Jin EH
PB
Park B
KY
Kim YS
CE
Choe EK
CS
Choi SH
KJ
Kim JS
JS
Jung SA
Chapter II

Abstract

Summary of the research findings

Introduction: The male-predominant sex difference through the spectrum of erosive esophagitis to Barrett's esophagus is widely known. We conducted a genome-wide association study (GWAS) stratified by sex for identifying factors that can predict the endoscopically diagnosed erosive esophagitis.

493 Korean ancestry male cases, 123 Korean ancestry female cases, 1,777 Korean ancestry male controls, 1,227 Korean ancestry female controls

Chapter III

Study Statistics

Key metrics and study information

4242
Total Participants
GWAS
Study Type
Yes
Replicated
100 Korean ancestry male cases, 32 Korean ancestry female cases, 297 Korean ancestry male controls, 193 Korean ancestry female controls
Replication Participants
East Asian
Ancestry
Republic of Korea
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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