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GWAS Study

Association of OPRM1 Functional Coding Variant With Opioid Use Disorder: A Genome-Wide Association Study.

Zhou H, Rentsch CT, Cheng Z et al.

32492095 PubMed ID
GWAS Study Type
476650 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

ZH
Zhou H
RC
Rentsch CT
CZ
Cheng Z
KR
Kember RL
NY
Nunez YZ
SR
Sherva RM
TJ
Tate JP
DC
Dao C
XK
Xu K
PR
Polimanti R
FL
Farrer LA
JA
Justice AC
KH
Kranzler HR
GJ
Gelernter J
Chapter II

Abstract

Summary of the research findings

Importance: With the current opioid crisis, it is important to improve understanding of the biological mechanisms of opioid use disorder (OUD).

10,544 European ancestry cases, 72,163 European ancestry controls, 5,212 African American cases, 26,876 African American controls

Chapter III

Study Statistics

Key metrics and study information

476650
Total Participants
GWAS
Study Type
Yes
Replicated
748 European ancestry cases, 361,107 European ancestry controls
Replication Participants
European, African American or Afro-Caribbean
Ancestry
U.K., U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

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