Heritability and genome-wide association analyses of fasting plasma glucose in Chinese adult twins.
Wang W, Zhang C, Liu H et al.
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Abstract
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Currently, diabetes has become one of the leading causes of death worldwide. Fasting plasma glucose (FPG) levels that are higher than optimal, even if below the diagnostic threshold of diabetes, can also lead to increased morbidity and mortality. Here we intend to study the magnitude of the genetic influence on FPG variation by conducting structural equation modelling analysis and to further identify specific genetic variants potentially related to FPG levels by performing a genome-wide association study (GWAS) in Chinese twins.
382 Chinese ancestry twin pairs
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