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GWAS Study

Genetic association of a gain of function interferon gamma receptor 1 (IFNGR1) polymorphism and the intergenic region LNCAROD/DKK1 with Behçet's disease.

Ortiz Fernández L, Coit P, Yilmaz V et al.

33393726 PubMed ID
GWAS Study Type
8982 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

OF
Ortiz Fernández L
CP
Coit P
YV
Yilmaz V
YS
Yentür SP
AF
Alibaz-Oner F
AK
Aksu K
EE
Erken E
DN
Düzgün N
KG
Keser G
CA
Cefle A
YA
Yazici A
EA
Ergen A
AE
Alpsoy E
SC
Salvarani C
CB
Casali B
KB
Kısacık B
KI
Kötter I
HJ
Henes J
ÇM
Çınar M
SA
Schaefer A
NR
Nohutcu RM
ZA
Zhernakova A
WC
Wijmenga C
TF
Takeuchi F
HS
Harihara S
KT
Kaburaki T
MM
Messedi M
SY
Song YW
KT
Kaşifoğlu T
CF
Carmona FD
GJ
Guthridge JM
JJ
James JA
MJ
Martin J
GE
González Escribano MF
SG
Saruhan-Direskeneli G
DH
Direskeneli H
SA
Sawalha AH
Chapter II

Abstract

Summary of the research findings

Objective: Behçet's disease is a complex systemic inflammatory vasculitis of incompletely understood etiology. This study was undertaken to investigate genetic associations with Behçet's disease in a diverse multiethnic population.

2,344 Turkish ancestry cases, 1,920 Turkish ancestry controls, 437 European ancestry cases, 3,325 European ancestry controls, 312 East Asian ancestry cases, 398 East Asian ancestry controls, 104 Tunisian ancestry cases, 142 Tunisian ancestry controls

Chapter III

Study Statistics

Key metrics and study information

8982
Total Participants
GWAS
Study Type
No
Replicated
European, Other, Greater Middle Eastern (Middle Eastern, North African or Persian), East Asian
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.