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GWAS Study

Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies.

Traylor M, Persyn E, Tomppo L et al.

33773637 PubMed ID
GWAS Study Type
225419 Participants
169 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

TM
Traylor M
PE
Persyn E
TL
Tomppo L
KS
Klasson S
AV
Abedi V
BM
Bakker MK
TN
Torres N
LL
Li L
BS
Bell S
RL
Rutten-Jacobs L
TD
Tozer DJ
GC
Griessenauer CJ
ZY
Zhang Y
PA
Pedersen A
SP
Sharma P
JJ
Jimenez-Conde J
RT
Rundek T
GR
Grewal RP
LA
Lindgren A
MJ
Meschia JF
SV
Salomaa V
HA
Havulinna A
KC
Kourkoulis C
CK
Crawford K
MS
Marini S
MB
Mitchell BD
KS
Kittner SJ
RJ
Rosand J
DM
Dichgans M
JC
Jern C
SD
Strbian D
FI
Fernandez-Cadenas I
ZR
Zand R
RY
Ruigrok Y
RN
Rost N
LR
Lemmens R
RP
Rothwell PM
AC
Anderson CD
WJ
Wardlaw J
LC
Lewis CM
MH
Markus HS
Chapter II

Abstract

Summary of the research findings

The genetic basis of lacunar stroke is poorly understood, with a single locus on 16q24 identified to date. We sought to identify novel associations and provide mechanistic insights into the disease.

6,030 European ancestry cases, 248,929 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

225419
Total Participants
GWAS
Study Type
No
Replicated
European, African American or Afro-Caribbean, Hispanic or Latin American
Ancestry
Netherlands, Sweden, U.S., Belgium, Finland, Poland, Italy, U.K., Australia, Germany, Spain
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

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