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The impact of single-nucleotide polymorphisms on intravesical recurrence after bacillus Calmette-Guérin therapy for non-muscle invasive bladder cancer in a genome-wide association study.

Nagakawa S, Shiota M, Fujimoto N et al.

34215507 PubMed ID
GWAS Study Type
91 Participants
34 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

NS
Nagakawa S
SM
Shiota M
FN
Fujimoto N
YY
Yamamoto Y
BL
Blas L
TS
Tsukahara S
MT
Matsumoto T
KE
Kashiwagi E
TA
Takeuchi A
IJ
Inokuchi J
UT
Uchiumi T
MH
Matsuyama H
EM
Eto M
Chapter II

Abstract

Summary of the research findings

Objective: Bacillus Calmette-Guérin (BCG) instillation therapy is widely used to reduce intravesical recurrence in non-muscle invasive bladder cancer (NMIBC). In this study, we aimed to reveal the genetic variations associated with intravesical recurrence after BCG therapy for NMIBC in a genome-wide association study (GWAS).

14 Japanese ancestry individuals with recurrence, 30 Japanese ancestry individuals without recurrence

Chapter III

Study Statistics

Key metrics and study information

91
Total Participants
GWAS
Study Type
Yes
Replicated
29 Japanese ancestry individuals with recurrence, 18 Japanese ancestry individuals without recurrence
Replication Participants
East Asian
Ancestry
Japan
Recruitment Country
Chapter IV

AI-Generated Summary

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