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GWAS Study

Admixture mapping reveals the association between Native American ancestry at 3q13.11 and reduced risk of Alzheimer's disease in Caribbean Hispanics.

Horimoto ARVR, Xue D, Thornton TA et al.

34217363 PubMed ID
GWAS Study Type
2565 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

HA
Horimoto ARVR
XD
Xue D
TT
Thornton TA
BE
Blue EE
Chapter II

Abstract

Summary of the research findings

Genetic studies have primarily been conducted in European ancestry populations, identifying dozens of loci associated with late-onset Alzheimer's disease (AD). However, much of AD's heritability remains unexplained; as the prevalence of AD varies across populations, the genetic architecture of the disease may also vary by population with the presence of novel variants or loci.

1,174 Caribbean Hispanics ancestry cases, 1,391 Caribbean Hispanics ancestry controls

Chapter III

Study Statistics

Key metrics and study information

2565
Total Participants
GWAS
Study Type
No
Replicated
Hispanic or Latin American
Ancestry
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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