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GWAS Study

Characterizing the Genetic Architecture of Parkinson's Disease in Latinos.

Loesch DP, Horimoto ARVR, Heilbron K et al.

34227697 PubMed ID
GWAS Study Type
442253 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

LD
Loesch DP
HA
Horimoto ARVR
HK
Heilbron K
SE
Sarihan EI
IM
Inca-Martinez M
ME
Mason E
CM
Cornejo-Olivas M
TL
Torres L
MP
Mazzetti P
CC
Cosentino C
SE
Sarapura-Castro E
RA
Rivera-Valdivia A
MA
Medina AC
DE
Dieguez E
RV
Raggio V
LA
Lescano A
TV
Tumas V
BV
Borges V
FH
Ferraz HB
RC
Rieder CR
SA
Schumacher-Schuh A
SB
Santos-Lobato BL
VC
Velez-Pardo C
JM
Jimenez-Del-Rio M
LF
Lopera F
MS
Moreno S
CP
Chana-Cuevas P
FW
Fernandez W
AG
Arboleda G
AH
Arboleda H
AC
Arboleda-Bustos CE
YD
Yearout D
ZC
Zabetian CP
CP
Cannon P
TT
Thornton TA
OT
O'Connor TD
MI
Mata IF
Chapter II

Abstract

Summary of the research findings

Objective: This work was undertaken in order to identify Parkinson's disease (PD) risk variants in a Latino cohort, to describe the overlap in the genetic architecture of PD in Latinos compared to European-ancestry subjects, and to increase the diversity in PD genome-wide association (GWAS) data.

807 Latino cases, 690 Latino controls

Chapter III

Study Statistics

Key metrics and study information

442253
Total Participants
GWAS
Study Type
Yes
Replicated
1,234 Latino cases, 439,522 Latino controls
Replication Participants
Hispanic or Latin American
Ancestry
Colombia, Uruguay, Brazil, Chile, Peru
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

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