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GWAS Study

Genome-Wide Association Study Identifies a Functional <i>SIDT2</i> Variant Associated With HDL-C (High-Density Lipoprotein Cholesterol) Levels and Premature Coronary Artery Disease.

León-Mimila P, Villamil-Ramírez H, Macías-Kauffer LR et al.

34233476 PubMed ID
GWAS Study Type
4751 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

LP
León-Mimila P
VH
Villamil-Ramírez H
ML
Macías-Kauffer LR
JL
Jacobo-Albavera L
LB
López-Contreras BE
PR
Posadas-Sánchez R
PC
Posadas-Romero C
RS
Romero-Hidalgo S
MS
Morán-Ramos S
DM
Domínguez-Pérez M
OM
Olivares-Arevalo M
LP
López-Montoya P
NR
Nieto-Guerra R
AV
Acuña-Alonzo V
MG
Macín-Pérez G
BR
Barquera-Lozano R
DB
Del-Río-Navarro BE
GI
González-González I
CF
Campos-Pérez F
GF
Gómez-Pérez F
VV
Valdés VJ
SA
Sampieri A
RJ
Reyes-García JG
CM
Carrasco-Portugal MDC
FF
Flores-Murrieta FJ
AC
Aguilar-Salinas CA
VG
Vargas-Alarcón G
SD
Shih D
MP
Meikle PJ
CA
Calkin AC
DB
Drew BG
VL
Vaca L
LA
Lusis AJ
HA
Huertas-Vazquez A
VT
Villarreal-Molina T
CS
Canizales-Quinteros S
Chapter II

Abstract

Summary of the research findings

Objective: Low HDL-C (high-density lipoprotein cholesterol) is the most frequent dyslipidemia in Mexicans, but few studies have examined the underlying genetic basis. Our purpose was to identify genetic variants associated with HDL-C levels and cardiovascular risk in the Mexican population.

2,335 Mexican ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

4751
Total Participants
GWAS
Study Type
Yes
Replicated
2,114 Mexican ancestry individuals, 302 Totonac and Nahua ancestry individuals
Replication Participants
Hispanic or Latin American, Native American
Ancestry
Mexico
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.