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Associations between age of menarche and genetic variation in women of African descent: genome-wide association study and polygenic score analysis.

Scannell Bryan M, Ogundiran T, Ojengbede O et al.

34706928 PubMed ID
GWAS Study Type
3145 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SB
Scannell Bryan M
OT
Ogundiran T
OO
Ojengbede O
ZW
Zheng W
BW
Blot W
DS
Domcheck S
HA
Hennis A
NB
Nemesure B
AS
Ambs S
OO
Olopade OI
HD
Huo D
Chapter II

Abstract

Summary of the research findings

Introduction: Many diseases of adulthood are associated with a woman's age at menarche. Genetic variation affects age at menarche, but it remains unclear whether in women of African ancestry the timing of menarche is regulated by genetic variants that were identified in predominantly European and East Asian populations.

3,145 African American, African Barbadian or Nigerian ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

3145
Total Participants
GWAS
Study Type
No
Replicated
African American or Afro-Caribbean, Sub-Saharan African
Ancestry
U.S., Barbados, Nigeria
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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