Whole-exome sequencing reveals genetic variations in humans with differential sensitivity to sevoflurane：A prospective observational study.
Wei Y, Zhang D, Zuo Y
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The anesthesia sensitivity is heterogeneous both in animals and humans, while the underlying molecular mechanism has not yet been determined. Here, for the first time, we conducted a prospective observational study to test whether genetic variations contribute to the differential sensitivity to sevoflurane in humans.
500 East Asian ancestry individuals
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