Genome-wide association studies in non-anxiety individuals identified novel risk loci for depression.
Cheng B, Qi X, Meng P et al.
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Depression is a debilitating mental disorder that often coexists with anxiety. The genetic mechanisms of depression and anxiety have considerable overlap, and studying depression in non-anxiety samples could help to discover novel gene. We assess the genetic variation of depression in non-anxiety samples, using genome-wide association studies (GWAS) and linkage disequilibrium score regression (LDSC).
59,334 European ancestry cases, 19,805 European ancestry controls
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