Cold-induced vasodilation response in a Japanese cohort: insights from cold-water immersion and genome-wide association studies.
Yasukochi Y, Sera T, Kohno T et al.
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Abstract
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Cold-induced vasodilation (CIVD) occurs after blood vessels in the skin are constricted due to local cold exposure. Although many CIVD studies have been conducted, the underlying molecular mechanisms are yet to be clarified. Therefore, we explored genetic variants associated with CIVD response using the largest-scale dataset reported to date in a CIVD study involving wavelet analysis; thus, the findings improve our understanding of the molecular mechanisms that regulate the CIVD response.
94 Japanese ancestry individuals
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