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A quantitative trait GWAS on lens thickness identifies novel risk loci on <i>PTPRM</i> in the narrow angle individuals susceptible to PACG.

Chakraborty S, Sharma A, Pal S et al.

36927043 PubMed ID
GWAS Study Type
329 Participants
64 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CS
Chakraborty S
SA
Sharma A
PS
Pal S
SA
Sharma A
SR
Sihota R
BS
Bhattacharjee S
AM
Acharya M
Chapter II

Abstract

Summary of the research findings

Purpose: PACG is one of the leading causes of blindness where lens thickness is a major risk factor for narrow-angle individuals. To our knowledge, no literature has been reported on candidate gene for lens thickness as a quantitative trait (QT). Here, we performed a genome-wide association analysis on lens thickness in the narrow-angle individuals.

240 Indian ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

329
Total Participants
GWAS
Study Type
Yes
Replicated
89 individuals
Replication Participants
South Asian
Ancestry
India
Recruitment Country
Chapter IV

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