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GWAS Study

Overlap of Genetic Loci for Central Serous Chorioretinopathy With Age-Related Macular Degeneration.

Rämö JT, Abner E, van Dijk EHC et al.

37079300 PubMed ID
GWAS Study Type
344013 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

RJ
Rämö JT
AE
Abner E
VD
van Dijk EHC
WX
Wang X
BJ
Brinks J
NT
Nikopensius T
NM
Nõukas M
MH
Marjonen H
SK
Silander K
JS
Jukarainen S
KT
Kiiskinen T
CS
Choi SH
KR
Kajanne R
MJ
Mehtonen J
PP
Palta P
LS
Lubitz SA
KK
Kaarniranta K
SL
Sobrin L
KM
Kurki M
YS
Yzer S
EP
Ellinor PT
ET
Esko T
DM
Daly MJ
DH
den Hollander AI
PA
Palotie A
TJ
Turunen JA
BC
Boon CJF
RE
Rossin EJ
Chapter II

Abstract

Summary of the research findings

Importance: Central serous chorioretinopathy (CSC) is a serous maculopathy of unknown etiology. Two of 3 previously reported CSC genetic risk loci are also associated with AMD. Improved understanding of CSC genetics may broaden our understanding of this genetic overlap and unveil mechanisms in both diseases.

552 Finnish ancestry cases, 343,461 Finnish ancestry controls

Chapter III

Study Statistics

Key metrics and study information

344013
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Finland, Estonia
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

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