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Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for BMI in adulthood.

Hawkes G, Beaumont RN, Tyrrell J et al.

37280435 PubMed ID
GWAS Study Type
441761 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

HG
Hawkes G
BR
Beaumont RN
TJ
Tyrrell J
PG
Power GM
WA
Wood A
LM
Laakso M
FS
Fernandes Silva L
BM
Boehnke M
YX
Yin X
RT
Richardson TG
SG
Smith GD
FT
Frayling TM
Chapter II

Abstract

Summary of the research findings

Aims/hypothesis: Determining how high BMI at different time points influences the risk of developing type 2 diabetes and affects insulin secretion and insulin sensitivity is critical.

441,761 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

441761
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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