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GWAS Study

Association of non-high-density lipoprotein cholesterol trajectories with the development of non-alcoholic fatty liver disease: an epidemiological and genome-wide association study.

Lee JH, Kim J, Kim JO et al.

37403158 PubMed ID
GWAS Study Type
2203 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

LJ
Lee JH
KJ
Kim J
KJ
Kim JO
KY
Kwon YJ
Chapter II

Abstract

Summary of the research findings

Non-alcoholic fatty liver disease (NAFLD) shares common risk factors with cardiovascular diseases. Effects of longitudinal trends in non-high-density lipoprotein (non-HDL) cholesterol on NAFLD development are not understood. This study aimed to assess the relationship between non-HDL cholesterol trajectories and the incidence of NAFLD and to identify genetic differences contributing to NAFLD development between non-HDL cholesterol trajectory groups.

666 Korean ancestry cases, 1,537 Korean ancestry controls

Chapter III

Study Statistics

Key metrics and study information

2203
Total Participants
GWAS
Study Type
No
Replicated
East Asian
Ancestry
Republic of Korea
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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