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GWAS Study

Genome-wide meta-analysis identifies ancestry-specific loci for Alzheimer's disease.

Ge YJ, Chen SD, Wu BS et al.

39023044 PubMed ID
GWAS Study Type
1417 Participants
184 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

GY
Ge YJ
CS
Chen SD
WB
Wu BS
ZY
Zhang YR
WJ
Wang J
HX
He XY
LW
Liu WS
CY
Chen YL
OY
Ou YN
SX
Shen XN
HY
Huang YY
GY
Gan YH
YL
Yang L
ML
Ma LZ
MY
Ma YH
CK
Chen KL
CS
Chen SF
CM
Cui M
TL
Tan L
DQ
Dong Q
ZQ
Zhao QH
WY
Wang YJ
JJ
Jia JP
YJ
Yu JT
Chapter II

Abstract

Summary of the research findings

Introduction: Alzheimer's disease (AD) is a devastating neurological disease with complex genetic etiology. Yet most known loci have only identified from the late-onset type AD in populations of European ancestry.

630 Chinese ancestry cases, 787 Chinese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

1417
Total Participants
GWAS
Study Type
Yes
Replicated
up to 1,595 Chinese ancestry cases, up to 2,474 Chinese ancestry controls, up to 21,982 European ancestry cases, up to 41,944 European ancestry controls
Replication Participants
East Asian, European
Ancestry
China
Recruitment Country
Chapter IV

AI-Generated Summary

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