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GWAS Study

Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization.

Willems SM, Ng NHJ, Fernandez J et al.

39280063 PubMed ID
GWAS Study Type
1784 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

WS
Willems SM
NN
Ng NHJ
FJ
Fernandez J
FR
Fine RS
WE
Wheeler E
WJ
Wessel J
KH
Kitajima H
MG
Marenne G
SX
Sim X
YH
Yaghootkar H
WS
Wang S
CS
Chen S
CY
Chen Y
CY
Chen YI
GN
Grarup N
LR
Li-Gao R
VT
Varga TV
AJ
Asimit JL
FS
Feng S
SR
Strawbridge RJ
KE
Kleinbrink EL
AT
Ahluwalia TS
AP
An P
AE
Appel EV
AD
Arking DE
AJ
Auvinen J
BL
Bielak LF
BN
Bihlmeyer NA
BJ
Bork-Jensen J
BJ
Brody JA
CA
Campbell A
CA
Chu AY
DG
Davies G
DA
Demirkan A
FJ
Floyd JS
GF
Giulianini F
GX
Guo X
GS
Gustafsson S
JA
Jackson AU
JJ
Jakobsdottir J
JM
Järvelin MR
JR
Jensen RA
KS
Kanoni S
KS
Keinanen-Kiukaanniemi S
LM
Li M
LY
Lu Y
LJ
Luan J
MA
Manning AK
MJ
Marten J
MK
Meidtner K
MD
Mook-Kanamori DO
MT
Muka T
PG
Pistis G
PB
Prins B
RK
Rice KM
SS
Sanna S
SA
Smith AV
SJ
Smith JA
SL
Southam L
SH
Stringham HM
TV
Tragante V
VD
van der Laan SW
WH
Warren HR
YJ
Yao J
YA
Yiorkas AM
ZW
Zhang W
ZW
Zhao W
GM
Graff M
HH
Highland HM
JA
Justice AE
ME
Marouli E
MC
Medina-Gomez C
AS
Afaq S
AW
Alhejily WA
AN
Amin N
AF
Asselbergs FW
BL
Bonnycastle LL
BM
Bots ML
BI
Brandslund I
CJ
Chen J
DJ
Danesh J
DM
de Mutsert R
DA
Dehghan A
ET
Ebeling T
EP
Elliott P
FA
Farmaki AE
FJ
Faul JD
FP
Franks PW
FS
Franks S
FA
Fritsche A
GA
Gjesing AP
GM
Goodarzi MO
GV
Gudnason V
HG
Hallmans G
HT
Harris TB
HK
Herzig KH
HM
Hivert MF
JT
Jørgensen T
JM
Jørgensen ME
JP
Jousilahti P
KE
Kajantie E
KM
Karaleftheri M
KS
Kardia SLR
KL
Kinnunen L
KH
Koistinen HA
KP
Komulainen P
KP
Kovacs P
KJ
Kuusisto J
LM
Laakso M
LL
Lange LA
LL
Launer LJ
LA
Leong A
LJ
Lindström J
MF
Manning Fox JE
MS
Männistö S
MN
Maruthur NM
ML
Moilanen L
MA
Mulas A
NM
Nalls MA
NM
Neville M
PJ
Pankow JS
PA
Pattie A
PE
Petersen ERB
PH
Puolijoki H
RA
Rasheed A
RP
Redmond P
RF
Renström F
RM
Roden M
SD
Saleheen D
SJ
Saltevo J
SK
Savonen K
SS
Sebert S
ST
Skaaby T
SK
Small KS
SA
Stančáková A
SJ
Stokholm J
SK
Strauch K
TE
Tai ES
TK
Taylor KD
TB
Thuesen BH
TA
Tönjes A
TE
Tsafantakis E
TT
Tuomi T
TJ
Tuomilehto J
UM
Uusitupa M
VM
Vääräsmäki M
VI
Vaartjes I
ZM
Zoledziewska M
AG
Abecasis G
BB
Balkau B
BH
Bisgaard H
BA
Blakemore AI
BM
Blüher M
BH
Boeing H
BE
Boerwinkle E
BK
Bønnelykke K
BE
Bottinger EP
CM
Caulfield MJ
CJ
Chambers JC
CD
Chasman DI
CC
Cheng CY
CF
Collins FS
CJ
Coresh J
CF
Cucca F
DB
de Borst GJ
DI
Deary IJ
DG
Dedoussis G
DP
Deloukas P
DR
den Ruijter HM
DJ
Dupuis J
EM
Evans MK
FE
Ferrannini E
FO
Franco OH
GH
Grallert H
HT
Hansen T
HA
Hattersley AT
HC
Hayward C
HJ
Hirschhorn JN
IA
Ikram A
IE
Ingelsson E
KF
Karpe F
KK
Kaw KT
KW
Kiess W
KJ
Kooner JS
KA
Körner A
LT
Lakka T
LC
Langenberg C
LL
Lind L
LC
Lindgren CM
LA
Linneberg A
LL
Lipovich L
LC
Liu CT
LJ
Liu J
LY
Liu Y
LR
Loos RJF
MP
MacDonald PE
MK
Mohlke KL
MA
Morris AD
MP
Munroe PB
MA
Murray A
PS
Padmanabhan S
PC
Palmer CNA
PG
Pasterkamp G
PO
Pedersen O
PP
Peyser PA
PO
Polasek O
PD
Porteous D
PM
Province MA
PB
Psaty BM
RR
Rauramaa R
RP
Ridker PM
RO
Rolandsson O
RP
Rorsman P
RF
Rosendaal FR
RI
Rudan I
SV
Salomaa V
SM
Schulze MB
SR
Sladek R
SB
Smith BH
ST
Spector TD
SJ
Starr JM
SM
Stumvoll M
VD
van Duijn CM
WM
Walker M
WN
Wareham NJ
WD
Weir DR
WJ
Wilson JG
WT
Wong TY
ZE
Zeggini E
ZA
Zonderman AB
RJ
Rotter JI
MA
Morris AP
BM
Boehnke M
FJ
Florez JC
MM
McCarthy MI
MJ
Meigs JB
MA
Mahajan A
SR
Scott RA
GA
Gloyn AL
BI
Barroso I
Chapter II

Abstract

Summary of the research findings

Genome-wide association studies for glycemic traits have identified hundreds of loci associated with these biomarkers of glucose homeostasis. Despite this success, the challenge remains to link variant associations to genes, and underlying biological pathways.

1,784 African American individuals

Chapter III

Study Statistics

Key metrics and study information

1784
Total Participants
GWAS
Study Type
No
Replicated
African American or Afro-Caribbean, European, East Asian, Hispanic or Latin American, South Asian
Ancestry
U.S., Sweden, Finland, Denmark, U.K., Germany, Republic of Ireland, Switzerland, Iceland, Spain, Greece, Netherlands, Austria, Italy, France, Serbia, Croatia, Pakistan, Singapore
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.