Evidence of survival bias in the association between <i>APOE-Є4</i> and age at ischemic stroke onset.
von Berg J, McArdle PF, Häppölä P et al.
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Abstract
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Introduction: Large genome-wide association studies (GWASs) using case-control study designs have now identified tens of loci associated with ischemic stroke (IS). As a complement to these studies, we performed GWAS in a case-only design to identify loci influencing the age at onset (AAO) of ischemic stroke.
10,857 European ancestry individuals
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