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GWAS Study

Exploring multi-omics and clinical characteristics linked to accelerated biological aging in Asian women of reproductive age: insights from the S-PRESTO study.

Chen L, Tan KM, Xu J et al.

39516835 PubMed ID
GWAS Study Type
882 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CL
Chen L
TK
Tan KM
XJ
Xu J
MP
Mishra P
MS
Mir SA
GM
Gong M
NK
Narasimhan K
NB
Ng B
LJ
Lai JS
TM
Tint MT
CS
Cai S
SS
Sadananthan SA
MN
Michael N
YJ
Yaligar J
VS
Velan SS
LM
Leow MKS
TK
Tan KH
CJ
Chan J
MM
Meaney MJ
CS
Chan SY
CY
Chong YS
EJ
Eriksson JG
Chapter II

Abstract

Summary of the research findings

Phenotypic age (PhenoAge), a widely used marker of biological aging, has been shown to be a robust predictor of all-cause mortality and morbidity in different populations. Existing studies on biological aging have primarily focused on individual domains, resulting in a lack of a comprehensive understanding of the multi-systemic dysregulation that occurs in aging.

667 Chinese ancestry women, 134 Malay ancestry women, 81 Indian ancestry women

Chapter III

Study Statistics

Key metrics and study information

882
Total Participants
GWAS
Study Type
No
Replicated
East Asian, South East Asian, South Asian
Ancestry
Singapore
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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