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Genetic modifiers of asthma response to air pollution in children: An African ancestry GWAS and PM<sub>2.5</sub> polygenic risk score study.

Kelchtermans J, March ME, Mentch F et al.

39725137 PubMed ID
GWAS Study Type
3870 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KJ
Kelchtermans J
MM
March ME
MF
Mentch F
QH
Qu H
LY
Liu Y
NK
Nguyen K
HH
Hakonarson H
Chapter II

Abstract

Summary of the research findings

Rationale: Ambient air pollution (AAP) is linked to asthma outcomes, but predicting individual risk remains challenging. Understanding genetic contributors to AAP sensitivity may help overcome this gap.

1,462 African ancestry cases, 2,408 African ancestry controls

Chapter III

Study Statistics

Key metrics and study information

3870
Total Participants
GWAS
Study Type
No
Replicated
African American or Afro-Caribbean, African unspecified
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

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