Genome-wide meta-analysis in lichen sclerosus identifies 14 genomic risk loci.
Dand N, Rayinda T, Silz E et al.
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Lichen sclerosus (LS) is a common and highly debilitating chronic inflammatory dermatosis that primarily affects genital skin in both females and males. Despite the utility of large genetic studies to reveal pathogenic mechanisms and suggest novel therapeutic targets, the genetic basis of LS remains largely unstudied.
6,681 European ancestry female cases, 407,255 European ancestry female controls
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