Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project.
Fox CS, Heard-Costa N, Cupples LA et al.
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Abstract
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Obesity is related to multiple cardiovascular disease (CVD) risk factors as well as CVD and has a strong familial component. We tested for association between SNPs on the Affymetrix 100K SNP GeneChip and measures of adiposity in the Framingham Heart Study.
1,079 European ancestry individuals from 310 families
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