Menu
GWAS Study

ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients.

Ochi H, Maekawa T, Abe H et al.

20637204 PubMed ID
GWAS Study Type
923 Participants
Scroll to explore
Chapter I

Publication Details

Comprehensive information about this research publication

Authors

OH
Ochi H
MT
Maekawa T
AH
Abe H
HY
Hayashida Y
NR
Nakano R
KM
Kubo M
TT
Tsunoda T
HC
Hayes CN
KH
Kumada H
NY
Nakamura Y
CK
Chayama K
Chapter II

Abstract

Summary of the research findings

Background & aims: Ribavirin-induced anemia is one of the major causes of discontinuation and dose reduction during anti-hepatitis C virus therapy. Factors influencing this anemia, especially host genetic factors, are poorly understood. In this study we investigated predictive factors in hepatitis C virus patients treated with combination therapy.

453 Japanese ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

923
Total Participants
GWAS
Study Type
Yes
Replicated
470 Japanese ancestry individuals
Replication Participants
East Asian
Ancestry
Japan
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.