A genome-wide association scan on estrogen receptor-negative breast cancer.
Li J, Humphreys K, Darabi H et al.
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Introduction: Breast cancer is a heterogeneous disease and may be characterized on the basis of whether estrogen receptors (ER) are expressed in the tumour cells. ER status of breast cancer is important clinically, and is used both as a prognostic indicator and treatment predictor. In this study, we focused on identifying genetic markers associated with ER-negative breast cancer risk.
617 European ancestry cases, 4,583 European ancestry controls
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