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GWAS Study

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.

Wild PS, Zeller T, Schillert A et al.

21606135 PubMed ID
GWAS Study Type
59789 Participants
117 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

WP
Wild PS
ZT
Zeller T
SA
Schillert A
SS
Szymczak S
SC
Sinning CR
DA
Deiseroth A
SR
Schnabel RB
LE
Lubos E
KT
Keller T
EM
Eleftheriadis MS
BC
Bickel C
RH
Rupprecht HJ
WS
Wilde S
RH
Rossmann H
DP
Diemert P
CL
Cupples LA
PC
Perret C
EJ
Erdmann J
SK
Stark K
KM
Kleber ME
ES
Epstein SE
VB
Voight BF
KK
Kuulasmaa K
LM
Li M
SA
Schäfer AS
KN
Klopp N
BP
Braund PS
SH
Sager HB
DS
Demissie S
PC
Proust C
KI
König IR
WH
Wichmann HE
RW
Reinhard W
HM
Hoffmann MM
VJ
Virtamo J
BM
Burnett MS
SD
Siscovick D
WP
Wiklund PG
QL
Qu L
EM
El Mokthari NE
TJ
Thompson JR
PA
Peters A
SA
Smith AV
YE
Yon E
BJ
Baumert J
HC
Hengstenberg C
MW
März W
AP
Amouyel P
DJ
Devaney J
SS
Schwartz SM
SO
Saarela O
MN
Mehta NN
RD
Rubin D
SK
Silander K
HA
Hall AS
FJ
Ferrieres J
HT
Harris TB
MO
Melander O
KF
Kee F
HH
Hakonarson H
SJ
Schrezenmeir J
GV
Gudnason V
ER
Elosua R
AD
Arveiler D
EA
Evans A
RD
Rader DJ
IT
Illig T
SS
Schreiber S
BJ
Bis JC
AD
Altshuler D
KM
Kavousi M
WJ
Witteman JC
UA
Uitterlinden AG
HA
Hofman A
FA
Folsom AR
BM
Barbalic M
BE
Boerwinkle E
KS
Kathiresan S
RM
Reilly MP
OC
O'Donnell CJ
SN
Samani NJ
SH
Schunkert H
CF
Cambien F
LK
Lackner KJ
TL
Tiret L
SV
Salomaa V
MT
Munzel T
ZA
Ziegler A
BS
Blankenberg S
Chapter II

Abstract

Summary of the research findings

eQTL analyses are important to improve the understanding of genetic association results. We performed a genome-wide association and global gene expression study to identify functionally relevant variants affecting the risk of coronary artery disease (CAD).

2,078 European ancestry cases, 2,953 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

59789
Total Participants
GWAS
Study Type
Yes
Replicated
19,350 European ancestry cases, 35,408 European ancestry controls
Replication Participants
European
Ancestry
Germany, Finland, Sweden, U.S., U.K., France
Recruitment Country
Chapter IV

AI-Generated Summary

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