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GWAS Study

Association between single nucleotide polymorphism-genotype and outcome of patients with chronic lymphocytic leukemia in a randomized chemotherapy trial.

Wade R, Di Bernardo MC, Richards S et al.

21659360 PubMed ID
GWAS Study Type
736 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

WR
Wade R
DB
Di Bernardo MC
RS
Richards S
RD
Rossi D
CD
Crowther-Swanepoel D
GG
Gaidano G
OD
Oscier DG
CD
Catovsky D
HR
Houlston RS
Chapter II

Abstract

Summary of the research findings

There is variability in the outcome of patients with chronic lymphocytic leukemia with apparently the same stage of disease. Identifying genetic variants that influence patients' outcome and response to treatment may provide important insights into the biology of the disease.

356 European ancestry cases

Chapter III

Study Statistics

Key metrics and study information

736
Total Participants
GWAS
Study Type
Yes
Replicated
380 European ancestry cases
Replication Participants
European
Ancestry
U.K., Italy
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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