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GWAS Study

Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients.

Huang RS, Johnatty SE, Gamazon ER et al.

21705454 PubMed ID
GWAS Study Type
139 Participants
65 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

HR
Huang RS
JS
Johnatty SE
GE
Gamazon ER
IH
Im HK
ZD
Ziliak D
DS
Duan S
ZW
Zhang W
KE
Kistner EO
CP
Chen P
BJ
Beesley J
MS
Mi S
OP
O'Donnell PH
FY
Fraiman YS
DS
Das S
CN
Cox NJ
LY
Lu Y
MS
Macgregor S
GE
Goode EL
VR
Vierkant RA
FB
Fridley BL
HE
Hogdall E
KS
Kjaer SK
JA
Jensen A
MK
Moysich KB
GM
Grasela M
OK
Odunsi K
BR
Brown R
PJ
Paul J
LD
Lambrechts D
DE
Despierre E
VI
Vergote I
GJ
Gross J
KB
Karlan BY
DA
Defazio A
CG
Chenevix-Trench G
DM
Dolan ME
Chapter II

Abstract

Summary of the research findings

Purpose: Cell-based approaches were used to identify genetic markers predictive of patients' risk for poor response prior to chemotherapy.

87 European ancestry lymphoblastoid cell lines

Chapter III

Study Statistics

Key metrics and study information

139
Total Participants
GWAS
Study Type
Yes
Replicated
52 European ancestry lymphoblastoid cell lines
Replication Participants
European
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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