Association of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia.
Bakken TE, Bloss CS, Roddey JC et al.
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Abstract
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Context: Cortical thickness is a highly heritable structural brain measurement, and reduced thickness has been associated with schizophrenia, bipolar disorder, and decreased cognitive performance among healthy control individuals. Identifying genes that contribute to variation in cortical thickness provides a means to elucidate some of the biological mechanisms underlying these diseases and general cognitive abilities.
573 European ancestry cases, 481 European ancestry controls
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