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GWAS Study

Genome-wide association study of urinary albumin excretion rate in patients with type 1 diabetes.

Sandholm N, Forsblom C, Mäkinen VP et al.

24595857 PubMed ID
GWAS Study Type
5675 Participants
66 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SN
Sandholm N
FC
Forsblom C
MV
Mäkinen VP
MA
McKnight AJ
OA
Osterholm AM
HB
He B
HV
Harjutsalo V
LR
Lithovius R
GD
Gordin D
PM
Parkkonen M
SM
Saraheimo M
TL
Thorn LM
TN
Tolonen N
WJ
Wadén J
TJ
Tuomilehto J
LM
Lajer M
AE
Ahlqvist E
MA
Möllsten A
MM
Marcovecchio ML
CJ
Cooper J
DD
Dunger D
PA
Paterson AD
ZG
Zerbini G
GL
Groop L
TL
Tarnow L
MA
Maxwell AP
TK
Tryggvason K
GP
Groop PH
Chapter II

Abstract

Summary of the research findings

Aims/hypothesis: An abnormal urinary albumin excretion rate (AER) is often the first clinically detectable manifestation of diabetic nephropathy. Our aim was to estimate the heritability and to detect genetic variation associated with elevated AER in patients with type 1 diabetes.

1,925 European ancestry cases

Chapter III

Study Statistics

Key metrics and study information

5675
Total Participants
GWAS
Study Type
Yes
Replicated
3,750 European ancestry cases
Replication Participants
European
Ancestry
Sweden, Italy, U.K., Republic of Ireland, Finland
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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