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GWAS Study

Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.

Guan W, Steffen BT, Lemaitre RN et al.

24823311 PubMed ID
GWAS Study Type
8631 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

GW
Guan W
SB
Steffen BT
LR
Lemaitre RN
WJ
Wu JHY
TT
Tanaka T
MA
Manichaikul A
FM
Foy M
RS
Rich SS
WL
Wang L
NJ
Nettleton JA
TW
Tang W
GX
Gu X
BS
Bandinelli S
KI
King IB
MB
McKnight B
PB
Psaty BM
SD
Siscovick D
DL
Djousse L
CY
Chen YI
FL
Ferrucci L
FM
Fornage M
MD
Mozafarrian D
TM
Tsai MY
SL
Steffen LM
Chapter II

Abstract

Summary of the research findings

Omega6 (n6) polyunsaturated fatty acids (PUFAs) and their metabolites are involved in cell signaling, inflammation, clot formation, and other crucial biological processes. Genetic components, such as variants of fatty acid desaturase (FADS) genes, determine the composition of n6 PUFAs.

8,631 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

8631
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.S., Italy
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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