Menu
Currency
GWAS Study

CKM and LILRB5 are associated with serum levels of creatine kinase.

Dubé MP, Zetler R, Barhdadi A et al.

25214527 PubMed ID
GWAS Study Type
6801 Participants
83 Views
Scroll to explore
Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DM
Dubé MP
ZR
Zetler R
BA
Barhdadi A
BA
Brown AM
MI
Mongrain I
NV
Normand V
LN
Laplante N
AG
Asselin G
ZY
Zada YF
PS
Provost S
BJ
Bergeron J
KS
Kouz S
DR
Dufour R
DA
Diaz A
DD
de Denus S
TJ
Turgeon J
RE
Rhéaume E
PM
Phillips MS
TJ
Tardif JC
Chapter II

Abstract

Summary of the research findings

Statins (HMG-CoA reductase inhibitors) are the most prescribed class of lipid-lowering drugs for the treatment and prevention of cardiovascular disease. Creatine kinase (CK) is a commonly used biomarker to assist in the diagnosis of statin-induced myotoxicity but the normal range of CK concentrations is wide, which limits its use as a diagnostic biomarker.

3,412 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

6801
Total Participants
GWAS
Study Type
Yes
Replicated
3,389 European ancestry individuals
Replication Participants
European
Ancestry
Canada
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

AI Summary In Progress

Our AI-generated summary of this publication is being prepared. Please check back soon.