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GWAS Study

Novel genetic variants modify the effect of smoking on carotid plaque burden in Hispanics.

Della-Morte D, Wang L, Beecham A et al.

24954085 PubMed ID
GWAS Study Type
929 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DD
Della-Morte D
WL
Wang L
BA
Beecham A
BS
Blanton SH
ZH
Zhao H
SR
Sacco RL
RT
Rundek T
DC
Dong C
Chapter II

Abstract

Summary of the research findings

Background and purpose: Smoking greatly increases the risk of atherosclerotic plaque and the effect may vary from individual to individual. A genome-wide scan was performed for smoking×single nucleotide polymorphism (SNP) interactions on carotid plaque burden (CPB) to identify the potential genetic moderators in Hispanics.

665 Hispanic individuals

Chapter III

Study Statistics

Key metrics and study information

929
Total Participants
GWAS
Study Type
Yes
Replicated
264 Hispanic indivduals
Replication Participants
Hispanic or Latin American
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

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