Novel genetic variants modify the effect of smoking on carotid plaque burden in Hispanics.
Della-Morte D, Wang L, Beecham A et al.
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Abstract
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Background and purpose: Smoking greatly increases the risk of atherosclerotic plaque and the effect may vary from individual to individual. A genome-wide scan was performed for smoking×single nucleotide polymorphism (SNP) interactions on carotid plaque burden (CPB) to identify the potential genetic moderators in Hispanics.
665 Hispanic individuals
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