A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain.
Meng W, Deshmukh HA, van Zuydam NR et al.
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Neuropathic pain, caused by a lesion or a disease affecting the somatosensory system, is one of the most common complications in diabetic patients. The purpose of this study is to identify genetic factors contributing to this type of pain in a general diabetic population.
572 European ancestry cases, 2,491 European ancestry controls
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