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GWAS Study

Genetic variant predicts bevacizumab-induced hypertension in ECOG-5103 and ECOG-2100.

Schneider BP, Li L, Shen F et al.

25117820 PubMed ID
GWAS Study Type
642 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SB
Schneider BP
LL
Li L
SF
Shen F
MK
Miller KD
RM
Radovich M
OA
O'Neill A
GR
Gray RJ
LD
Lane D
FD
Flockhart DA
JG
Jiang G
WZ
Wang Z
LD
Lai D
KD
Koller D
PJ
Pratt JH
DC
Dang CT
ND
Northfelt D
PE
Perez EA
ST
Shenkier T
CM
Cobleigh M
SM
Smith ML
RE
Railey E
PA
Partridge A
GJ
Gralow J
SJ
Sparano J
DN
Davidson NE
FT
Foroud T
SG
Sledge GW
Chapter II

Abstract

Summary of the research findings

Bevacizumab has broad anti-tumour activity, but substantial risk of hypertension. No reliable markers are available for predicting bevacizumab-induced hypertension.

255 European ancestry cases, 387 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

642
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.