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GWAS Study

A genome-wide association study of radiotherapy induced toxicity in head and neck cancer patients identifies a susceptibility locus associated with mucositis.

Schack LMH, Naderi E, Fachal L et al.

35039627 PubMed ID
GWAS Study Type
1780 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SL
Schack LMH
NE
Naderi E
FL
Fachal L
DL
Dorling L
LC
Luccarini C
DA
Dunning AM
OE
Ong EHW
CM
Chua MLK
LJ
Langendijk JA
AB
Alizadeh BZ
OJ
Overgaard J
EJ
Eriksen JG
AC
Andreassen CN
AJ
Alsner J
Chapter II

Abstract

Summary of the research findings

Purpose: A two-stage genome-wide association study was carried out in head and neck cancer (HNC) patients aiming to identify genetic variants associated with either specific radiotherapy-induced (RT) toxicity endpoints or a general proneness to develop toxicity after RT.

1,183 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

1780
Total Participants
GWAS
Study Type
Yes
Replicated
597 Dutch ancestry individuals
Replication Participants
European
Ancestry
Denmark
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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