Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.
Sung YJ, de las Fuentes L, Schwander KL et al.
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Abstract
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Cardiovascular diseases are among the most significant health problems in the United States. Blood pressure (BP) variability has a genetic component, and most of the genetic variance remains to be identified. One promising strategy for gene discovery is genome-wide analysis of interactions between single nucleotide polymorphisms (SNPs) and environmental factors related to cardiovascular diseases.
Up to 6,889 individuals
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