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GWAS Study

Identification of a Hashimoto thyroiditis susceptibility locus via a genome-wide comparison with Graves' disease.

Oryoji D, Ueda S, Yamamoto K et al.

25429627 PubMed ID
GWAS Study Type
990 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

OD
Oryoji D
US
Ueda S
YK
Yamamoto K
YN
Yoshimura Noh J
OK
Okamura K
NM
Noda M
WN
Watanabe N
YA
Yoshihara A
IK
Ito K
ST
Sasazuki T
Chapter II

Abstract

Summary of the research findings

Hashimoto thyroiditis (HT) and Graves' disease (GD) share some immunological features. Determining the genetic basis that distinguishes HT from GD is key for a better understanding of the differences between these two related diseases.

263 Japanese ancestry Hashimoto thyroiditis cases, 260 Japanese ancestry Graves’ disease cases

Chapter III

Study Statistics

Key metrics and study information

990
Total Participants
GWAS
Study Type
Yes
Replicated
181 Japanese ancestry Hashimoto thyroiditis cases, 286 Japanese ancestry Graves’ disease cases
Replication Participants
East Asian
Ancestry
Japan
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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