Association of genetic variants for plasma LRG1 with rapid decline in kidney function in patients with type 2 diabetes.
Gurung RL, Dorajoo R, M Y et al.
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Abstract
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Context: Elevated levels of plasma leucine-rich α-2-glycoprotein 1 (LRG1), a component of transforming growth factor beta signaling, are associated with development and progression of chronic kidney disease in patients with type 2 diabetes (T2D). However, whether this relationship is causal is uncertain.
983 Chinese ancestry individuals, 420 Malay ancestry individuals, 478 Indian ancestry individuals
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