Genetic and Metabolic Determinants of Plasma Levels of ANGPTL8.
Oldoni F, Bass K, Kozlitina J et al.
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Abstract
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Context: ANGPTL8 (A8) plays a key role in determining the tissue fate of circulating triglycerides (TGs). Plasma A8 levels are associated with several parameters of glucose and TG metabolism, but the causality of these relationships and the contribution of genetic variants to differences in A8 levels have not been explored.
1,779 African American individuals, 1,022 European ancestry individuals, 589 Hispanic or Latin American individuals, 67 individuals
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