Genome-wide association analysis of plasma B-type natriuretic peptide in blacks: the Jackson Heart Study.
Musani SK, Fox ER, Kraja A et al.
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Abstract
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Numerous experimental studies suggest that B-type natriuretic peptide (BNP) is cardioprotective; however, in clinical studies, higher plasma BNP concentrations have been associated with incident cardiovascular disease and higher left ventricular mass. Genetic association studies may allow us to determine the true causal directions without confounding by compensatory mechanisms.
2,790 Black individuals
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